We help companies solve complex scientific challenges
Reliable image analysis software
TotalLab is a global pioneer and leader in software development for image analysis.
We were founded in 2013 when we evolved out of Nonlinear Dynamics, after it was acquired by Waters Corporation. We have maintained and built upon our ability to create bespoke software and OEM software for data analysis, enabling labs to have confidence in the results of their analysis.
The evolution of gel electrophoresis software
Following the acquisition of Nonlinear Dynamics, we started to work more closely with the pharmaceutical industry. We focused on our 2D software, SpotMap, which was developed to meet the time critical needs of this industry. Our software enables academic researchers and those in industry to make informed choices, for instance when choosing antibodies for host cell protein detection in advanced therapeutics. Since its launch in 2015 it has now become the industry standard for HCP coverage analysis.
We also offer SameSpots, a 2D gel analysis statistics software package which identifies differential protein expression and enables you to easily export ‘spots’ of interest for further analysis with mass spectrometry.
CLIQS is our 1D gel image analysis software which enables evaluation of DNA, RNA and protein samples, including Western Blot analysis.
Based in the UK with a global reach
Based in Newcastle upon Tyne in North East England, we work with clients around the world, providing solutions and expertise in image analysis. We also support companies in achieving and maintaining regulatory compliance, including 21 CFR part 11 and EU Annex 11. Learn more about our GxP solution and its integration with our 1D and 2D analysis software here.
We pride ourselves on being responsive and reactive to the questions and requirements of our clients and partners. Through listening to our customers and applying feedback, we have continuously improved and developed our portfolio.
And as we have decades of both industry and software experience, our clients feel confident and safe in the knowledge that our products are tried and tested to deliver fast, accurate and reliable results via an easy-to-use platform.
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Resources
How to Read Dot Blot Results
Learn to read dot blot results with easy steps and tips. Understand protein detection, antibody specificity, and optimize lab results
Find Out MoreWhat are DNA Microarray Assays?
Discover what DNA microarray assays are, how they work, and their applications in genomics and personalized medicine.
Find Out MoreWhat is Host Cell Protein?
Discover what host cell proteins (HCPs) are, why they matter in biologic drug development, and how they’re analyzed for safety. Learn about common HCP analysis methods, challenges, and strategies to manage risks, with insights on tools from Totallab
Find Out MoreHow to Read Western blot
Learn how to read Western blot results with easy, actionable steps. From sample preparation to data analysis, TotalLab's guide covers everything you need for accurate protein detection. Perfect for researchers and lab professionals!
Find Out MoreSpotMap Examples and Evidence
We work closely with our customers from across the globe to ensure they get the best from SpotMap. Please find here a collection of examples and evidence of SpotMap being used by various Industrial and Academic customers and presented at conferences worldwide.
Image Capture Guide
Good image capture is critical to guarantee optimal performance of automated image analysis packages and generate reliable scientific data. This technical document provides a brief guide to the range of different image acquisition devices currently in use for gel applications, defines some the important technical factors required to generate digital images of a quality suitable for automated image analysis and recommendations for producing good 2D gel images.
Find Out More