We help companies solve complex scientific challenges

Reliable image analysis software

TotalLab is a global pioneer and leader in software development for image analysis.

We were founded in 2013 when we evolved out of Nonlinear Dynamics, after it was acquired by Waters Corporation. We have maintained and built upon our ability to create bespoke software and OEM software for data analysis, enabling labs to have confidence in the results of their analysis.

The evolution of gel electrophoresis software

Following the acquisition of Nonlinear Dynamics, we started to work more closely with the pharmaceutical industry. We focused on our 2D software, SpotMap, which was developed to meet the time critical needs of this industry. Our software enables academic researchers and those in industry to make informed choices, for instance when choosing antibodies for host cell protein detection in advanced therapeutics. Since its launch in 2015 it has now become the industry standard for HCP coverage analysis.

We also offer SameSpots, a 2D gel analysis statistics software package which identifies differential protein expression and enables you to easily export ‘spots’ of interest for further analysis with mass spectrometry.

CLIQS is our 1D gel image analysis software which enables evaluation of DNA, RNA and protein samples, including Western Blot analysis.

Based in the UK with a global reach

Based in Newcastle upon Tyne in North East England, we work with clients around the world, providing solutions and expertise in image analysis. We also support companies in achieving and maintaining regulatory compliance, including 21 CFR part 11 and EU Annex 11. Learn more about our GxP solution and its integration with our 1D and 2D analysis software here.

We pride ourselves on being responsive and reactive to the questions and requirements of our clients and partners. Through listening to our customers and applying feedback, we have continuously improved and developed our portfolio.

And as we have decades of both industry and software experience, our clients feel confident and safe in the knowledge that our products are tried and tested to deliver fast, accurate and reliable results via an easy-to-use platform.

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Resources

Equipment & Reagents Required for Pulsed Field Gel Electrophoresis (PFGE)

Explore TotalLab's advanced PFGE equipment list designed for life scientists. Discover how our pulsed-field gel electrophoresis systems can deliver precise DNA separation for your research needs

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HCP Coverage Analysis Using 2D Western Blot

Discover how 2D Western blotting enhances Host Cell Protein (HCP) coverage analysis in biopharmaceutical research. Learn the key steps, from protein separation and transfer to PVDF membranes to antibody staining and data analysis. See how TotalLab's SpotMap software improves HCP detection and quantification, ensuring regulatory compliance and accurate results.

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TotalLab’s SpotMap: Automated 2D Western Blot Analysis Software for HCP Detection

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How To Calculate Western Blot Normalization

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What is the Precipitin Test?

Discover the science behind antigen-antibody precipitin reactions and how to analyze them using TotalLab's Phoretix 1D Software

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How to Read Dot Blot Results

Learn to read dot blot results with easy steps and tips. Understand protein detection, antibody specificity, and optimize lab results

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